Abstract The serendipitous discovery that inhibiting type 5 phosphodiesterase (PDE5) using sildenafil, a potent PDE5 inhibitor (PDE5i) initially developed for cardioprotection, introduced the possibility of orally managing erectile dysfunction (ED) led to an increase in research data, which are currently considered groundbreaking for the new discip
The evolution of transcriptional regulators through the recruitment of DNA-binding domains by enzymes is a widely Candles held notion.However, few experimental approaches have directly addressed this hypothesis.Here we report the reconstruction of a plausible pathway for the evolution of an enzyme into a transcriptional regulator.The BzdR protein i
Growing awareness for occupational safety in the welding environment needs a sustainable welding system.Welding gases releases toxic tiny particles and gases that inflict severe health consequences in the weld zone are unsolicited.Some of the other main adverse effects are lung disease, hemoptysis, pulmonary inflammation, pneumoconiosis, etc.GMAW p
The main objective of this paper is to evaluate the relative impact of financial sector development, government size and trade openness of a country on its economic growth.This is done to investigate which factors play more prominent role in leading the growth of the economy.Four ASEAN countries known for their similar economic orientation, namely
Abstract Objective: To describe the factors associated with dental caries among students from Santa Cruz do Sul, Rio Grande do Sul, Brazil.Methods: A cross-sectional study was conducted in a random sample of 623 students of both genders, aged 10-17 years old.Tooth decay was performed using the index of MASTER PREMIUM METAL CLIP COMB the World Healt